Hi Steve,
This natural gas hose fits the standard natural hose fittings used on gas grills. As far as we know, Weber grills use these standard quick disconnect fittings. The "quick disconnect" system has a connector with spring tension. You pull back on the connector to release or attach the hose from the grill. If that's what you have, you can feel confident in this replacement. We have sold this product to multiple Weber customers with natural gas grills including the E series.
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Answered by Grill Girl on Mar 3, 2021